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You might have consistency problems if you have: multiple datastores in multiple datacenters, without distributed transactions, and with the ability to alternately execute out of each datacenter; syncing protocols that can fail or sync stale data; distributed clients that cache data and then write old back to the central store; a NoSQL database that doesn't have transactions between updates of multiple related key-value records; application level integrity checks; client driven optimistic locking.
Sounds a lot like many evolving, loosely coupled, autonomous, distributed systems these days. How do you solve these consistency problems? Siddharth "Sid" Anand of Netflix talks about how they solved theirs in his excellent presentation, NoSQL @ Netflix : Part 1, given to a packed crowd at a Cloud Computing Meetup.
You might be inclined to say how silly it is to have these problems in the first place, but just hold on. See if you might share some of their problems, before getting all judgy: