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The most common complaint against NoSQL is that if you know how to write good SQL queries then SQL works fine. If SQL is slow you can always tune it and make it faster. A great example of this incremental improvement process was written up by StackExchange's Sam Saffron, in A day in the life of a slow page at Stack Overflow, where he shows through profiling and SQL tuning it was possible to reduce page load times from 630ms to 40ms for some pages and for other pages the improvement was 100x.
Sam provides a lot of wonderful detail of his tuning process, how it works, the thought process, the tools used, and the tradeoffs involved. Here's a short summary of the steps: