Recommend Scalable virus scanning for web-applications (Email)

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Hi, We're looking for a highly scalable way of scanning documents being uploaded and downloaded from our web application. I believe services like gmail and hotmail are using bespoke solutions from companies like Trend, but are there some quality "off the shelf" products out there that can easily be scaled out and have a "loose" API (HTTP based) for application integration? Once again, thanks for any input.


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